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Expected results: 5-10% body fat reduction over 12 weeks with proper nutrition and training

Li: Loss of lean body mass is a real concern, especially in older adults

Metformin: Mechanisms in Human Obesity and Weight Loss

Muscle loss can occur if: protein intake is low resistance training is limited weight loss occurs rapidly While the overall health benefits of weight loss can be significant, muscle plays an essential role in protecting the spine

Rather than focusing only on the number on the scale during your first week, look for other positive changeslike increased energy, better sleep, or improved moodthat show your body is responding to your personalized plan

1E) (overall P value = 0.5215, two-way ANOVA with repeated measures)