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DNMT1 is the most abundant DNMT in cells and, as previously described, is believed to act as the primary maintenance methyltransferase to methylate hemimethylated DNA after DNA replication and preserve parental DNA methylation patterns in daughter cells

The cystine-glutamate transporter enhancer N-acetyl-L-cysteine attenuates cocaine-induced changes in striatal dopamine but not self-administration in squirrel monkeys

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3-bromopyruvate also targeting HK2 is testified to ameliorate survival of ATC [271]

Many studies have highlighted amino acids essential for tumor growth, including glutamine, proline, and serine [2,3]

doi: 10.1038/nrurol.2017.69 30 AitkenRJ