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24 More potent ferroptosis inhibitors may also protect due to off-target effects

FRDA is caused by a homozygous guanineadenineadenine (GAA) repeat expansion within the first intron of the frataxin gene ( FXN ) located on the long arm of chromosome 9 [83]

Pancreatic cancer promotes tumor innervation by secreting nerve growth factor (NGF), compensating for insufficient exogenous nutrients by utilizing serine released from nerve axons (73), thereby establishing an adaptive loop of metabolism-microenvironmental remodeling

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2020;12(572):eaaz2841
