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Description
The absence of standardized outcome measures across studies further complicates evidence synthesis and interpretation

Vidal-Alaball J, Butler CC, Cannings-John R, Goringe A, Hood K, McCaddon A, McDowell I, Papaioannou A
This distinguishes it from GLP-1 agonists like semaglutide, which produce greater weight loss but carry a risk of muscle wasting

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doi: 10.1021/jacs.9b02822
There's nothing like Matter of Fact
