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GST expression and/or activity of specific isoforms is lost in some individuals with allelic variation

Using the FerrDb database, we analyzed the GEO dataset GSE44619

Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasion

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In order to shed more light on this interesting finding, we solved the atomic structure of CsiD in complex with its substrate (GA), its product (SA) as well as in complex with the KG-analog N-oxalylglycine (NOG) as inhibitor, by X-ray crystallography (Fig

Anonymous (2019) GeneTree Image