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This has in fact been done in mice (401)

Biochemical Society Symposium

Key Ingredients of Glutathione Skin Whitening Soaps Glutathione: Function: Glutathione is a potent antioxidant that helps to lighten the skin by inhibiting melanin production
Knocking down enolase1 expression resulted in increased sensitivity of gastric cancer cells to cisplatin (Qian et al., 2017)
