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An important finding for researchers monitoring metabolic health: 88% of CagriSema participants who had prediabetes at baseline returned to normoglycemia by the end of the REDEFINE 1 trial

10.1038/s41564-018-0129-3 Nat

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30 Three phases of colchicine poisoning include: 30 Gastrointestinal phase (10 24 hours) including abdominal pain, nausea/vomiting and diarrhoea Multiorgan phase (2 7 days) can include a wide range of serious adverse effects including paralytic ileus, myopathy, myocardial toxicity and severe cardiovascular dysfunction, respiratory failure and blood dyscrasias Recovery phase in those who survive (within a few weeks) Colchicine is contraindicated in patients with severe renal or hepatic impairment, significant gastrointestinal or cardiac conditions or pre-existing blood dyscrasias