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It has been associated with nausea, flushing, changes in moles, priapism and case reports of more serious events, including renal infarction
In the body, cobalamin binds to a protein called transcobalamin II and enters tissue through its receptors
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220 Theoretical risks include health problems in offspring related to genetic and epigenetic effects of oxidative stress, which may occur as a result of the procedure or may be inherited

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It is important to note that the person applying methimazole should take care to not touch the methimazole solution, as it can be absorbed through the skin and cause low thyroid levels in humans