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Not all protocols include this dose level, and many physicians progress directly from 10 mg to 15 mg if further escalation is warranted

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The combination of fever, jaundice, and right upper quadrant pain (Charcot's triad) suggests cholangitis, a medical emergency requiring immediate care

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Values presented as percentage of total Adverse events are presented for all participants who were randomised and took at least one dose of treatment, regardless of whether they discontinued * For the T2D trial, this was limited to supraventricular arrhythmias and cardiac conduction disorders ** For the obesity trial these are presented as hepatic disorder / biliary disorder separately NA : Not applicable In the obesity trial, serious adverse events (SAEs) occurred in 4% of participants with retatrutide use overall (06% across groups) vs

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