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NIF, an antidiarrheal antibiotic, demonstrated efficacious suppression of STAT3 activation in cell lines of colorectal cancer, multiple myeloma, colon ulcer, and diabetic kidney tissues (Althagafy et al

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The clinical relevance of PDE5i has been proven in ischemia-reperfusion injury, pressure overload-induced hypertrophy, heart failure, myocardial ischemia (47, 48)

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In contrast to some porphyrias, there are no dermatological findings

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It plays an essential role in transporting long-chain fatty acids into the mitochondria of cells , where they are oxidized to produce energy

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doi: 10.3390/jcm11164713 [DOI] [PMC free article] [PubMed] [Google Scholar] 208

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