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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

doi: 10.1016/0167-0115(84)90028-4

many patients do well on a daily 50-150 microgram oral cyanocobalamin instead

J Neural Transm 121:12691272 [DOI] [PubMed] [Google Scholar] Liu D, Ke Z, Luo J (2017) Thiamine deficiency and neurodegeneration: the interplay among oxidative stress, endoplasmic reticulum stress, and autophagy

While it's speculated to be easier to absorb than cyanocobalamin, research hasn't shown a meaningful difference

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