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274 Similarity, in another clinical trials of SSc, the researchers found that rituximab (RTX) relieved symptoms of patients with SSc by upregulation of Dkk-1

It is known that glutathione may promote pheomelanin synthesis, inhibit intracellular melanogenic enzymes, and demonstrate antioxidative as well as antiaging effects [2, 3]

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10.1002/ajmg.c.30089 64 WangD.YeJ.ShiR.ZhaoB.LiuZ.LinW.et al (2022)

Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats
Pharmacol Ther 48, 357369 (1990)