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Also, oxaliplatin-induced mechanical hyperalgesia is reduced in germ-free mice and in mice pretreated with antibiotics, which further suggests that the gut microbiota promotes the development of oxaliplatin-induced mechanical hypersensitivity and neuroinflammation

Chauhan et al., 2012

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The oxidative respiration channel nicotinamide adenine dinucleotide reduces (NADH) and pyruvate to the mitochondria, which is facilitated by pyruvate dehydrogenase (PDH)

Es dient beim Energiestoffwechsel als Transporteur von Fettsuren zwischen Cytosol und den Mitochondrien