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At this level, the cells lose their nuclei and organelles, and become more specialized as they begin to die

& OKeeffe, G

It also explores specific pathways, including the role of systemic inflammation in BBB disruption and neuroinflammation, the impact of gut microbiota dysbiosis on intestinal permeability and translocation of microbial products, the contribution of oxidative stress to BBB damage, the potential involvement of the vagus nerve in transmitting signals from the gut to the brain, and the effects of altered gut microbial metabolite production on neuronal function

10.1016/j.cell.2012.03.042 21 DixonS