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[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Choi B.D., Yu X., Castano A.P., Bouffard A.A., Schmidts A., Larson R.C., Bailey S.R., Boroughs A.C., Frigault M.J., Leick M.B

Figure 3 3.2.1 Endothelial damage Endothelial integrity is crucial for maintaining the function of the BBB

The activated cells generate pro-inflammatory cytokines such as TNF, IL-1, and IL-6 which amplify inflammation as well as proteases including MMP-9 which cause elastin degradation and emphysema

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These toxic metals can contribute to various health concerns, including fatigue, cognitive issues, and immune dysfunction