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Impact of Intestinal Bacteria on Levodopa Pharmacokinetics in LCIG Therapy
coli isolates, supporting the idea that these locations are crucial for drug binding and are likely to evolve as resistance emerges (Marcusson et al., 2009
It is also in a phase III trial for advanced cholangiocarcinoma (NCT 02989857)
Kischkel FC
They include enzymatic degradation by proteases or peptidases, low permeability across the mucosal epithelium, and rapid clearance due to salivary dynamics
Aragons et al
