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Description
This section presents current neuron-targeted therapeutic strategies, organized along a conceptual axis from extracellular modulation (e.g., receptor activation and trophic signaling) to intracellular mechanisms (e.g., signal transduction, transcriptional regulation and metabolic support)

At the genetic level, it has been observed that the expression of Gln metabolism-related genes in tumor cells is significantly higher than that in CD8+ T cells, underscoring the metabolic advantage held by tumor cells (16)

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Ageing Res Rev 8:1830 Dantzer R, Kelley KW (2007) Twenty years of research on cytokine-induced sickness behavior

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