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[Abstract]2022 Nov 3;29(11):1531-1546.e7

BPC-157 and TB-500 operate through fundamentally different molecular mechanisms: BPC-157 modulates the nitric oxide system and upregulates growth factors including EGF, VEGF, and FGF-2 to promote cytoprotection and angiogenesis, while TB-500 sequesters G-actin monomers to regulate actin polymerization, cytoskeletal dynamics, and cell migration

Mild fatigue may occur

Neurological symptoms may also be observed such as: subacute mild encephalopathy, affecting memory & concentration, chronic mild axonal polyneuropathy, manifested as distal paresthesias, radicular pain (less common), some rare ones include encephalomyelitis & leukoencephalopathy

Reganold, J

Complement factors, especially alternative complement pathway genes, have been reported in the pathogenesis of AMD (Figure 4)