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Am J Physiol Regul Integr Comp Physiol 2009;296:R67R71

doi: 10.1016/j.jtauto.2021.100082
In the matrix, multiple enzymes work together to degrade misfolded, damaged, and oxidized proteins, as well as to turnover some metabolic enzymes, forming the CLPXP complex and Lon protease homolog (LONP)
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The impact can be significant, both mentally and physically

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