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For example, the administration of the insulin growth factor small-interfering RNA blocks KET antidepressant effects in the mouse learned helplessness model of depression (Zanos et al., 2016)

10.1038/s41598-022-09888-l PMID: 35388133 [DOI] [PMC free article] [PubMed] [Google Scholar] [94].Erol A, Karpyak VM

10.1039/b103668h [DOI] [Google Scholar] Sardar A

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[43] [56] [57] Randomized controlled trials of continuous stimulant therapy for the treatment of ADHD spanning 2 years have demonstrated treatment effectiveness and safety

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