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Filtration and centrifugation remove interferents

Using lipid nanoparticle-encapsulated siRNA to target and silence macrophage Cxcl2 markedly reduces myocardial neutrophil infiltration, diminishes inflammation, and reduces infarct size, concurrently demonstrating that aberrant macrophage chemotactic activity is a key target exacerbating post-inflammatory myocardial ischemic injury (33)

Yamanouchi, M

Recent preclinical studies have shown that targeting glutamine metabolism provides therapeutic opportunities 15,19

GSH depletion does not induce mitochondrial superoxide or alter mitochondrial mass in RPE cells It has been suggested that mitochondria are predominant source of ROS upon H 2 O 2 -induced oxidative stress 7