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By providing a physiologically relevant alternative to 2D cultures and animal models, this study supports iHLO adoption for drug discovery and preclinical testing

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Role of AIF in caspase-dependent and caspase-independent cell death

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Despite the small size of the tri- and tetrapeptides, a property ultimately necessary for BBB permeability, these molecules were metabolically unstable and likely too hydrophilic to breach the BBB
