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The answer is: you need controlled trials

doi: 10.1016/j.fertnstert.2004.10.010

Especially not with protein

The transcription of NF-B-dependent genes influences the levels of ROS in the cell, and, in turn, the levels of NF-B activity are also regulated by the levels of ROS [35]

Mitochondrial function is dependent upon adequacy of all the B vitamins (Depeint et al., 2006)

Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China
