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10.7150/thno.100080 Theranostics
found that LPS stimulation led to an approximately 30-fold accumulation of succinate in mouse bone marrow-derived macrophages (BMDMs), which in turn specifically promoted the transcription and expression of IL-1 by inhibiting prolyl hydroxylase (PHD) and stabilizing HIF-1 ( During macrophage metabolic reprogramming, amino acid metabolism does not operate independently, but is embedded within the overall metabolic network
Apr 22 2024;19(1):31
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It converts food into energy, supports the brain and nerves, and helps form red blood cells that transport oxygen
[Google Scholar] 19.Lee J.W., Choi S.O., Felner E.I., Prausnitz M.R
