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Protein changes in senile dementia


Other (not necessarily mutually exclusive) theories of aminoglycoside-induced toxicity include free radical formation via binding of iron and subsequent formation of oxidative compounds, reversible blockade of sensory transduction by blocking calcium-sensitive potassium channels, and excessive N-methyl-D-aspartate (NMDA) receptor activation and excitotoxicity due to aminoglycoside agonist activity at the NMDA subtype of glutamate receptor (10

10.1016/j.cell.2013.12.010 164 ZeidanY
S-Glutathionylation occurs extensively in diseases characterized by oxidative stress, including cardiovascular diseases, cancer, lung diseases, neurodegenerative diseases, and cancer

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