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Improved Glucose and Lipid Metabolism : Experimental studies demonstrate that suppression of NNMT activity with 5-Amino-1MQ correlates with improved glucose tolerance and reduced hepatic lipid accumulation

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doi: 10.1038/s41375-019-0587-5 45 MorandiFMorandiBHorensteinALChillemiAQuaronaVZaccarelloGet al

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In the landmark STEP 1 clinical trial, participants using semaglutide 2.4mg achieved an average body weight reduction of approximately 15% at 68 weeks compared to 2.4% in the lifestyle-only group

Tang W, Zhang L, Zheng Y, Pan L, Niu T