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Interestingly, some clinical studies have shown that L-carnitine may also support heart muscle strength and help maintain healthy blood pressure levels, especially in individuals with a higher BMI

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Inhibiting the activity of system Xc- prevents the absorption of cystine, affects GSH synthesis, and subsequently reduces GPX4 activity (the membrane lipid-repair enzyme), thus reducing the cellular antioxidant capacity and promoting ferroptosis (Figure 1B) (Chen et al., 2021a

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One single nucleotide substitution predicts the substitution of the highly conserved Arg89 by Cys (BPGM Creteil I)