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4 The consequence is the evident gap between the theory (reestablished homeostasis, integrative beneficial effects) and the practical realization (limited beneficial activity of the given agent with the harmful effect as well)
Biochem Pharmacol 59(12):15631571 Kumagai Y, Lin LY, Schmitz DA, Cho AK (1991) Hydroxyl radical mediated demethylenation of (methylenedioxy)phenyl compounds

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