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Investigating Nonapoptotic Cell Death Using Chemical Biology approaches

Contraindications [edit] Contraindications include: [22] Known hypersensitivity to clomipramine, or any of the excipients or cross-sensitivity to tricyclic antidepressants of the dibenzazepine group Recent myocardial infarction Any degree of heart block or other cardiac arrhythmias Mania Severe liver disease Narrow angle glaucoma Untreated urinary retention It must not be given in combination or within 3 weeks before or after treatment with a monoamine oxidase inhibitor

Annu Rev Nutr 43(1):279300

On the other hand, an abuse of steroids can cause liver damage, kidney failure, depression and increased aggression

doi: 10.1042/AN20110011 83 NewsholmeP

Elevated dimethylarginine, ATP, cytokines, metabolic remodeling involving tryptophan metabolism and potential microglial inflammation characterize primary open angle glaucoma