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Lets say your body does not have access to carbohydrates maybe because youre following a low-carb diet your body can switch to using fats instead of carbs for fuel

2007 Aug;7(4):355-9

however, the in ovo supplementation of L-leucine was not able to mitigate these effects in the heat-stressed chickens (181)

It is a diverse family of substances with at least 28 distinct types identified in mammals, with types I, II, and III being the most prevalent forms in the human body [48, 49]