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In rare cases, you may need surgery or a type of medicine called a thrombolytic

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Therapeutic Effect of Anti-inflammatory Tripeptide Cream in Hand-Foot Syndrome/Skin Reaction Related to Anticancer Drugs: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial

This study had several limitations
These medications may reduce how long B12 remains in the body, requiring individuals to supplement more frequently to maintain appropriate levels
Avoid exposure to humidity or extreme temperatures
