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Prior to eventual internalization by distant immune cells, the formation of MVs, which also contain important immune-cell receptors and inhibitory complement receptors, may contribute to an immune or tolerogenic microenvironment for MM cells in the bone marrow (BM) niche [25] [26]

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When bacterial overgrowth damages the intestinal barrier, toxins such as lipopolysaccharides enter the bloodstream

2021;9(9):e3803

It applies to premature neonates under 37 weeks gestation who develop physiologic anemia from low iron stores, rapid growth, and blood draws in the NICU