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doi: 10.3389/fphar.2021.668418 52 MaQ.ZhaiR.XieX.ChenT.ZhangZ.LiuH.et al

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The findings of the aforementioned studies suggest that exploring the link between the MAPK signaling pathway and ferroptosis may reveal intervention targets for ferroptosis-related diseases

Defective Negative Regulation of Toll-like Receptor Signaling Contributes to Excessive TNF- Production in Myeloproliferative Neoplasm

Subsequent studies demonstrate that erastin inhibits cystine import and downstream glutathione synthesis, leading to deregulated cellular redox homeostasis and ultimately cell death (Dixon et al., 2012
