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The science of LL-37 revolves around its cationic, amphipathic structure, which allows it to selectively disrupt microbial membranes while simultaneously binding to host cell receptors to organize, regulate, and resolve the immune response and repair damaged tissue

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The overexpression of miR-21-3p correlates with the inhibition of critical neuronal and synaptic genes such as DLGAP1 , which decreased the expression of Protocadherin-19 ( PCDH19 ), associated with cognitive impairment