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Pro-apoptotic Activity of Inhibitory PAS Domain Protein (IPAS), a Negative Regulator of HIF-1, through Binding to Pro-survival Bcl-2 Family Proteins

doi: 10.3390/antiox13020207 7

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1 Introduction Diabetes is a common chronic disease with many complications, and its main characteristic is high glucose concentration in the blood, which is caused by absolute or relative insulin secretion insufficiency and/or insulin utilization disorder (1, 2)

Current progress in pharmacogenomics of Type 2 diabetes: a systemic overview

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