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New England Journal of Medicine, 384(11), 9891002

planning pregnancy soon Kidney disease (dehydration can worsen kidney function) Diabetic retinopathy if you have diabetes (eye monitoring may be needed) Use of insulin or sulfonylureas (risk of low blood sugar
The relative risk was 0.76, actually trending slightly lower than placebo, though not statistically significant
They both work best alongside lifestyle changes, including a reduced-calorie diet and more physical activity
Weeks 2 Through 4 at Starting Dose Good news: by your second injection at 0.25 mg, nausea often improves noticeably

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