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Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells

In a randomized, double-blind, placebo-controlled trial from Korea, Tak et al

PCOS women with insulin resistance have a higher accumulation of visceral fat, a surplus of androgens and experience more severe clinical symptoms, including hirsutism, acne, and ovulatory disorder, in contrast to PCOS women lacking insulin resistance [54]

Therefore, two may be better than one in this case, but do what's best for you

Protonate3D: assignment of ionization states and hydrogen coordinates to macromolecular structures

This study examined the hypothesis that GSH-deficiency induces epigenetic alterations of VD metabolism genes, which can reduce the circulating 25(OH)VD 3 levels in obesity