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Documented side effects are usually mild to moderate: Injection-site pain, redness, or bruising Flushing Increased heart rate Nausea or gastrointestinal upset Headache Urinary changes or a fishy body odor at higher choline doses Because these are compounded products, sterile technique, pharmacy sourcing, and formulation verification matter

Unfortunately, in cases where this does not happen and the symptom is untreated or unnoticed, it grows, penetrates deeper into the stomach, damaging its subsequent layers and blood vessels

Are they worried it may cut into the profits of their other drugs, such as NSAIDs, PPIs, and biologics

Safety as a dietary supplement is not yet fully understood

10.1016/j.cell.2005.02.034 136

J Alzheimers Dis 19:311323