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The combination of metabolic improvements positions GLP-1 receptor agonists as potentially valuable therapeutic agents for MASLD and NASH

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We need to push for more research, clinical trials, and conversations around how these medications could be used in ways we never thought possible

Biggest exits drive ecosystem confidence Mega rounds + pharma acquisitions of biotech send the strongest external signal that obesity remains a top-priority therapeutic area

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Inactivation of NF-kappaBp65 (RelA) in liver improved insulin sensitivity and inhibited cAMP/PKA pathway