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Given the vital role of Vit B12 in neural function, its deficiency may contribute to neurodegeneration and exacerbate motor and non-motor symptoms in PD patients

The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

[DOI] [PubMed] [Google Scholar] 128.Hoyer D., Clarke D.E., Fozard J.R., Hartig P.R., Martin G.R., Mylecharane E.J., Saxena P.R., Humphrey P.P

A subsequent study examined IN-exendin-4 benefits on severe MCI in a senescence-accelerated mouse (SAMP8) model

10mg As needed per protocol Upstream hormone trigger for natural testosterone and reproductive health

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