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Overall, these results showed that inhibition of anti-ferroptosis mechanisms enhanced the anti-leukemic activity of APR-246 in vivo

Therapeutic inhibition of ferroptosis in neurodegenerative disease

Possibly, this toxicity, in addition to lower esophageal sphincter and pyloric sphincter failure, involves sole NSAIDs-gastric ulcers, presenting with aspirin (and thereby, aspirin was used intragastrically) (14) and ibuprofen (10), as well as with those agents combining gastric and small intestine ulcers (i.e., diclofenac (9, 11))

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Pushing to 2.4mg purely because it is the "maximum" dose is not always the right move, especially if side effects significantly impact quality of life

The term folate should be used to refer only to the bioactive forms of folic acid, namely dihydrofolate (DHF) and tetrahydrofolate (THF) and their derivatives