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Since 24 h treatment of adipocytes with an NNMT inhibitor increased intracellular levels of SAM and NAD + , it is likely that prolonged exposures to NNMT inhibitor during differentiation may have resulted in significantly enhanced intracellular flux of SAM and NAD +

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doi: 10.1002/wnan.1798 79 FanY.ChenM.ZhangJ.MaincentP.XiaX.WuW

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Individualized assessment matters because peptides like kisspeptins influence GnRH secretion and ovarian reserve differently across patients

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