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Enzyme-Coupled Receptors This final set of receptors that we need to discuss is much more structurally variable compared to GPCRs, but they all have one very important thing in common: when the ligand binds to the receptor, an enzyme known as a kinase is activated

About this article Cite this article Smink, J.J., Leutz, A

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Steinberg, Department of Pharmacology, College of Physicians and Surgeons, Columbia University, 630 West 168 Street, New York, NY 10032, USA, [email protected] This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers