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2020, www.sciencedirect.com/science/article/abs/pii/S0976566220304409, Wen Ting Hao, et al

Ferroptosis has been implicated in a number of disorders such as neurodegenerative diseases (amyotrophic lateral sclerosis (ALS), Alzheimers disease (AD), Parkinsons disease (PD), and Huntingtons disease (HD), etc.), ischemia/reperfusion injury, and kidney degeneration

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Because of its unique physicochemical characteristics and the ease with which it may be transformed into a wide range of functionalized coumarins during synthesis, coumarin provides a privileged scaffold for medicinal chemists

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