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For the duration of the study, animals were singly housed in standard individually ventilated cages (Innovive, San Diego, CA) with nesting material enrichment (ALPHA-Twist

Post-mortem studies of brains from patients with HD have shown increased levels of DA and increased activity of tyrosine hydroxylase (TH), the rate-limiting enzyme in DA synthesis, in the striatum and SNc 3,4,5

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