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All enrolled participants were weight stable, free from acute or chronic diseases, and did not eat a diet or take medications that might interfere with outcome markers including antioxidant supplements, high intake of dietary polyphenols including coffee, or anti-inflammatory medications

Activated ECs exhibit impaired synthesis or release of EDRFs, resulting in sustained vasoconstriction, reduced vessel diameter, slowed blood flow and impaired pulmonary microcirculation

Kang et al., 2009

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doi: 10.1080/13543776.2020.1703952 71