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In addition, the C57BL/6J mice used for several of our in vivo studies of immune function harbour a spontaneous mutation within the nicotinamide nucleotide transhydrogenase ( Nnt ) gene, which encodes an enzyme that regulates mitochondrial redox homoeostasis

Since insulin resistance and progression to T2DM and metabolic syndrome are key aspects of MASH development, the results of the PIVENS trial cannot necessarily be generalized to this patient group

doi: 10.1038/nrclinonc.2016.60

This increase in blood flow can also contribute to elevation of body temperature and increased sweating in response to physical exertion

[Google Scholar] 130.Keller J, Couturier A, Haferkamp M, Most E, Eder K

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