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Opicapone reduces the expression of MMPs and gelatinase activity, which are responsible for the degradation of the ECM and increased BBB permeability

140 Cataract Cataract remains the leading cause of legal blindness worldwide, especially in low-income countries, where it accounts for 50% of all cases of blindness (Figure 3)

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In the univariate MR analysis, elevated bilirubin level was associated with decreased risk of ulcerative colitis (Odds ratio [OR] = 0.189, 95% confidence interval [CI]: 0.0720.492)

M1-like microglia are induced by IFN and LPS, signaling through various pathways like TLR4 and JAK/STAT 139 , 141