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Description

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Materials and methods We conducted a double-blind, two-cohort, parallel design, placebo-controlled study to evaluate the safety and efficacy of investigational LC (Carnipure tartrate), in its salt form, L carnitine L-tartrate (LCLT), in adults at risk of SARS-CoV-2-infection (Cohort 1) or disease progression (Cohort 2) in patients with SARS-CoV-2 infection

32 Neuroprotection measures Comatous children must be considered as having cerebral edema and treated accordingly: head raised at 30, neck in the neutral position, sedation and analgesia to avoid agitation, and mechanical ventilation according to coma severity

Several studies have identified an association between HA and VPA therapy [6, 9,10,11,12], with a number of risk factors including age [9], VPA dose and blood concentration [5, 13], and concomitant use of VPA with liver enzyme inducers such as phenobarbital (PB), phenytoin (PHT) and carbamazepine (CBZ) [6, 14]