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The optimal dosage can vary depending on individual needs and goals, but it's important not to exceed the recommended amount

TMA is then transferred via the bloodstream to the liver where it becomes oxidized into TMAO, primarily by the enzyme FMO3 [4]

It is not a true vitamin because it is also biosynthesized endogenously from dietary amino acids (methionin, lysine), especially in the liver and in the kidneys [29,30]

Supplementary information Supplementary Tables 15, Supplementary Figures 123 and Supplementary Methods (PDF 2144 kb) Rights and permissions About this article Cite this article Koeth, R., Wang, Z., Levison, B

(2019) International Society for Nutritional Psychiatry Research Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major Depressive Disorder

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